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Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells.
D'Souza A, Burch A, Dave KM, Sreeram A, Reynolds MJ, Dobbins DX, Kamte YS, Zhao W, Sabatelle C, Joy GM, Soman V, Chandran UR, Shiva SS, Quillinan N, Herson PS, Manickam DS. D'Souza A, et al. Among authors: dave km. J Control Release. 2021 Oct 10;338:505-526. doi: 10.1016/j.jconrel.2021.08.038. Epub 2021 Aug 24. J Control Release. 2021. PMID: 34450196 Free PMC article.
Mitochondria-containing extracellular vesicles (EV) reduce mouse brain infarct sizes and EV/HSP27 protect ischemic brain endothelial cultures.
Dave KM, Stolz DB, Venna VR, Quaicoe VA, Maniskas ME, Reynolds MJ, Babidhan R, Dobbins DX, Farinelli MN, Sullivan A, Bhatia TN, Yankello H, Reddy R, Bae Y, Leak RK, Shiva SS, McCullough LD, Manickam DS. Dave KM, et al. J Control Release. 2023 Feb;354:368-393. doi: 10.1016/j.jconrel.2023.01.025. Epub 2023 Jan 18. J Control Release. 2023. PMID: 36642252 Free PMC article.
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